The safety class for propane refrigerant R-290 is A3, which means it has no toxicity but high flammability. The safety class is determined by the ASHRAE Standard 34, which assigns a capital letter (A or B) for the toxicity level and a number (1, 2, or 3) for the flammability level of a refrigerant. Propane has a very low global warming potential and ozone depletion potential, but it also has a very low flash point and high auto ignition temperature, which make it highly flammable in the presence of ignition sources.References:Propane R-290 | Copeland US;R-290 Propane Refrigerant Fact & Info Sheet;Safety Data Sheet - Refrigerants; NFPA Fire Protection Handbook, 21st Edition, Chapter 3, Section 3.3.4.
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