Multiple-dose vials (MDVs)containpreservativesto inhibit microbial growth. These vials are designed formultiple withdrawalsover time, increasing the risk of contamination. Preservatives, such asbenzyl alcohol or phenol, help prevent bacterial or fungal contamination after repeated needle insertions.
A. stability and compatibility→ Incorrect. Preservatives do not inhibit drug stability; they prevent microbial contamination.
B. sorption and leaching→ Incorrect. Sorption (adsorption/absorption of drugs onto container surfaces) and leaching (release of chemicals from containers) are unrelated to preservatives.
D. synergistic reactions→ Incorrect. Synergistic reactions refer to drug interactions, not contamination prevention.
PTCB PTCE Exam Content Outline (Sterile and Non-Sterile Compounding)
USP <797> Guidelines for Sterile Compounding
American Society of Health-System Pharmacists (ASHP) Guidelines on Multiple-Dose Vials
Mosby’s Pharmacy Technician Exam Review
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