Pass the Medical Council of Canada MCCQE Part 1 MCCQE Questions and answers with ValidTests

One of the strongest modifiable risk factors for postoperative delirium in older adults is exposure to anticholinergic medications (e.g., diphenhydramine, certain antidepressants). Avoiding these can reduce delirium risk.

Toronto Notes 2023 – Geriatrics, “Delirium Prevention”:

“Avoid high-risk medications including anticholinergics, benzodiazepines, and narcotics if possible. Maintain orientation cues and adequate pain control.”

MCCQE1 Objectives (Medicine > Geriatrics > 41-1: Cognitive Impairment):

“Candidates must recognize predisposing factors for delirium and apply prevention strategies, including medication review.”

Opiates (B) should be used judiciously; untreated pain can also cause delirium. Cognitive screening (C) is helpful for baseline but does not prevent delirium. Benzodiazepines (D) increase delirium risk. Family involvement is actually helpful (E).

====================================================

A varicocele is a dilatation of the pampiniform plexus that presents with a “bag of worms” appearance, worsens with standing, and improves when lying down. It is most common on the left side due to anatomical drainage differences.

Toronto Notes 2023 – Urology, Scrotal Disorders:

“Varicoceles often present with a dull, aching pain and scrotal swelling that worsens when upright and disappears when supine.”

MCCQE1 Objectives – Internal Medicine > Urology:

“Candidates must recognize and diagnose varicocele by physical exam findings and typical symptom history.”

Cryptorchidism (A) refers to undescended testes. Torsion (B) presents acutely with severe pain. Hydrocele (C) transilluminates and is not posture-dependent. "Spermatocyte" (D) is not a clinical diagnosis.

====================================================

When elder neglect is suspected—especially in cases of self-neglect or unclear caregiver dynamics—the most important immediate step is to assess the patient’s decision-making capacity. If she lacks capacity, protective intervention is warranted.

Toronto Notes 2023 – Geriatrics, “Elder Abuse and Capacity Assessment”:

“Decision-making capacity must be assessed when a patient is refusing care despite evidence of harm or risk.”

MCCQE1 Objectives (ELOM > 90-1: Capacity and Consent):

“Candidates must assess capacity in elderly patients before attributing decisions to autonomy, particularly in complex care situations.”

Evaluating criminal records (B) or clutter (C) may be relevant later but do not take precedence over capacity assessment. Alcohol/substance use (D) and financial abuse (E) are differential concerns, not the critical first step.

Comprehensive and Detailed Explanation:

Basement apartments are often damp environments, increasing the risk of mold exposure. Mold is a well-known asthma trigger. Given the timing (autumn/winter) and environment change, mold allergy is the most likely cause.

Toronto Notes 2023 – Respirology / Allergy:

“Mold is a common indoor allergen, especially in damp environments. It frequently exacerbates asthma, particularly in fall/winter.”

MCCQE1 Objectives (Pediatrics > 75-2: Asthma Triggers):

“Candidates must identify common environmental triggers for asthma, including mold exposure in humid or poorly ventilated housing.”

Cat allergy (B) would have triggered earlier. Pollen (D) is less relevant in winter. Cold intolerance (E) is not a major asthma trigger without exercise. Fungal infection (A) is unlikely without systemic symptoms.

—

In Canada, a minor may consent to medical care if the physician believes they have the capacity to understand the nature, benefits, and risks. This is known as the “mature minor doctrine.” Capacity is based on understanding, not age.

Toronto Notes 2023 – ELOM, “Consent and Capacity” Section:

“A minor may consent to treatment if they demonstrate sufficient maturity and understanding. It is the physician’s responsibility to assess capacity prior to prescribing.”

MCCQE1 Objectives (ELOM > 99-3: Consent and Confidentiality):

“Candidates must assess the patient’s ability to understand and make informed decisions, regardless of age.”

Prescribing without assessment (B) is premature. Reporting to child services (A) is only necessary if there are signs of abuse or coercion. Parental involvement (C) is not mandatory. Refusal based on age (E) contradicts legal and ethical practice.

====================================================

This patient presents with signs of acute compartment syndrome (pain out of proportion, paresthesia, pallor, swelling, decreased pulses, and dark urine indicating rhabdomyolysis). Measuring compartment pressures is the diagnostic test of choice to confirm the diagnosis and guide urgent surgical fasciotomy.

Toronto Notes 2023 – Orthopedics:

“Acute compartment syndrome should be suspected in any patient with severe extremity pain, swelling, sensory deficits, and tense compartments. Confirm with compartment pressure measurements. Fasciotomy is indicated if pressure is >30 mmHg or within 30 mmHg of diastolic pressure.”

MCCQE1 Objectives (Surgery > 51-2: Limb Trauma):

“Candidates must diagnose acute compartment syndrome and initiate appropriate surgical referral after confirming with pressure measurements.”

Angiography and Doppler studies assess vascular compromise but are not the first step in suspected compartment syndrome. Fixing the hip (C) and testing myoglobin (E) are not diagnostic steps.

====================================================

In a euthyroid patient with an asymptomatic goiter or thyroid enlargement, the next step is a thyroid ultrasound to evaluate nodule size, composition, and features suggestive of malignancy.

Toronto Notes 2023 – Endocrinology, Thyroid Nodules and Goiter:

“TSH should be obtained first. If normal and there is a palpable mass or enlargement, ultrasound is indicated to evaluate for nodules and guide further testing (e.g., FNA).”

MCCQE1 Objectives – Internal Medicine > Endocrinology:

“Candidates must use thyroid ultrasound as the initial imaging study in the evaluation of thyroid enlargement or palpable nodules.”

T3/T4 (A) are not needed with normal TSH. FNA (D) is done if nodules are identified. CT (C) is used for retrosternal goiters or compressive symptoms. Calcium (E) is irrelevant here.

====================================================

Persistent postmenopausal bleeding requires thorough evaluation. An inadequate endometrial biopsy result does not rule out pathology. Hysteroscopy allows for direct visualization and targeted biopsy and is the gold standard when biopsy is non-diagnostic.

Toronto Notes 2023 – Gynecology, “Abnormal Uterine Bleeding and Endometrial Cancer” Section:

“Persistent bleeding with insufficient biopsy requires further evaluation, preferably via hysteroscopy and directed biopsy. This is especially important in patients on HRT or with risk factors for endometrial pathology.”

MCCQE1 Objectives (Obstetrics & Gynecology > 82-9: Postmenopausal Bleeding):

“Candidates must investigate abnormal bleeding in postmenopausal women with hysteroscopy when endometrial sampling is non-diagnostic.”

Changing hormones (A), reducing progestin (E), or performing colposcopy (C) are not appropriate without confirming the cause of bleeding.

====================================================

Persistent bloody diarrhea with negative stool cultures and ova/parasite testing in an older adult suggests inflammatory bowel disease (IBD) or another colitis such as ischemic or microscopic colitis. Colonoscopy is the best next diagnostic step to evaluate for ulcerative colitis, Crohn disease, ischemic colitis, or malignancy.

Toronto Notes 2023 – Gastroenterology, "Inflammatory Bowel Disease":

“Persistent bloody diarrhea with negative infectious work-up should prompt colonoscopic evaluation to rule out IBD or other forms of colitis.”

MCCQE1 Objectives (Internal Medicine > Gastrointestinal > 47-1):

“Candidates must assess and investigate chronic or persistent diarrhea. In the presence of red flag features such as bleeding, weight loss, or anemia, colonoscopy is indicated.”

Antibiotics (A) are not indicated with negative stool cultures. Observation (C) and loperamide (D) risk delaying diagnosis. Steroids (E) may be required later but only after confirmation of diagnosis.

The patient has chronic non-cancer pain with comorbid PTSD and alcohol misuse — high-risk factors for opioid use disorder. Before any opioid prescribing, a comprehensive interdisciplinary approach including mental health and substance use support is essential.

Toronto Notes 2023 – Pain Management and Addiction Medicine:

“In chronic pain patients with substance use or mental health comorbidities, refer to addiction/mental health services before considering opioid therapy.”

MCCQE1 Objectives (ELOM > 99-4: Safe Prescribing):

“Candidates must assess for substance use risk factors and manage chronic pain using a multidisciplinary approach.”

Imaging (A) is unlikely to alter management. Opioids (B, C) should not be first-line in this context. Cannabis (E) is not first-line and lacks robust evidence in complex chronic pain.